(CS-115) Assessing the clinical benefits of a novel antimicrobial gelling fiber containing POLYHEXAMETHYLENE BIGUANIDE

Friday, April 10, 2026

Rachel Burns, BSc

Introduction: A Polyhexamethylene biguanide (PHMB) -impregnated fiber dressing has been developed to deliver rapid antimicrobial action, patient comfort, and improved wound progression. This abstract reports real-world clinical feedback compared with dressings previously used on the same wounds, predominantly silver fiber products.

Methods:

A prospective clinical feedback programme was conducted across hospital and community wound care settings. Adult patients with acute or chronic wounds requiring antimicrobial intervention were managed with the PHMB Fiber dressing as part of routine care. Clinicians completed structured assessments evaluating antimicrobial response, wound progression, exudate handling, ease of dressing application and removal. Patient-reported pain during wear and at dressing change was collected. Data sets were compared descriptively with clinician feedback on prior dressings.

Results:

Clinicians observed rapid antimicrobial effects, with improvements in infection symptoms, slough and exudate, and peri-wound condition typically within 48 hours. Patients reported reduced pain during wear and removal, attributed to the dressing’s patented quilting design with PHMB and fluid handling. Accelerated healing progression, including earlier granulation and improved peri-wound integrity scored highly. Overall performance lead to 87% of clinicians preference PHMB Fiber dressing over Silver Fiber dressings, citing its balance of antimicrobial efficacy, comfort, and ease of use.

Antimicrobial stewardship (AMS) is central to modern wound management, promoting effective non-antibiotic strategies that minimise resistance risk while maintaining strong antimicrobial performance. Polyhexamethylene biguanide (PHMB) provides broad-spectrum activity with a favourable safety profile and low resistance potential.

Discussion: The PHMB fiber dressing aligns with AMS principles by providing fast, effective antimicrobial action without reliance on silver or antibiotic-based approaches. Clinical feedback demonstrates reduced pain and enhanced healing, supporting its value as an alternative to silver fiber dressings.